Pigmentation models and in vitro assays

Pigmentation model is based on human iPSC-derived melanocytes.
Identify active ingredients among hundreds on our innovative high-throughput assays.
Validate or study mechanism of action with dedicated bioassays.
Our high-throughput screening services for pigmentation claim :
Starting price at 4200€/96wp.
This is a photo of three womans with different skin color . Their different ethnic skins origins symbolize our various skin cells models for dermo-cosmetic industry.

Ethnic specific
claim validation

Caucasian,
Asian and
African
Check our recent publication in Experimental Dermatology,
A high-throughput screening platform for pigment regulating agents
using pluripotent stem cell derived melanocytes.
Pattern of the high-throughput Flow cytometry for sebocyte screening. First compound and cell addition in the 96 well plate, then automated Flow cytometry to identificate activity and last valide the mechanism of action

Overall Protocol for Pro/Depigmentation claims

Using High-Throughput Flow Cytometry

Pigmentation facts

Bioassays catalog for Pigmentation

Area
Name
Method
Endpoint
Ref.
Pigmentation
Melanin content
OD reading
Melanin concentration
MEL-MLN
Pigmentation
High-throughput flow cytometry assay
Flow cytometry
Pigmentation level
MEL-HTS
Pigmentation
Melanogenesis pathway assay
RT-qPCR
Relative expression level
MEL-MPA
Oxidative stress
Cellular oxidative stress
CellROX staining
Normalized fluorescence
MEL-CRX
Melanogenesis
mRNA expression of characterized markers
RT-qPCR
Relative expression level
MEL-RNA
Melanogenesis
Tyrosinase expression
Immunolabeling
Cell ratio intensity of staining
MEL-TYR
Melanogenesis
MITF expression
Immunolabeling
Cell ratio intensity of staining
MEL-MITF
Cell proliferation
Cell proliferation / Survival
Calcein AM - EthD1
Living cells / Dead cells
MEL-LCC
Do you have specific R&D needs ?

We are able to do custom-made bioassays for you.

Move your R&D forward
With our innovative, efficient and cost-effective bioassays and cell models
Get in touch